New views on pathogenesis and diagnosis of peritoneal carcinomatosis

Peritoneal metastasis occurs in a number of heterogeneous tumors originating from the ovaries, stomach, intestines, pancreas, lungs, breast, and melanoma. carcinomatosis significantly reduces overall survival. While being almost unresponsive to treatment, dissemination tumor cells along peritoneum aggravates course disease. Despite use locoregional peritoneal is still considered be an aggravating factor with poor prognosis. cannot defined as separate process its own biology oncogenesis due lack clear understanding molecular biological features metastasis, well generally recognized standards for diagnosis treatment malignant neoplasms various localizations. Addressing developing event will enhance morpho- strengthen search therapeutic, diagnostic preventive approaches management. Th e paper presents bibliographic study publications on exploring metastases sites, including abdominal pelvic organs. known mechanisms are characterized paper. Diagnostic were assessed compared. collected data analysis revealed main gaps oncogenesis.